PRP: Why the Details Matter

Platelet-rich plasma (PRP) injections are becoming more and more common. Patients with osteoarthritis, tennis or golfer’s elbow, partial rotator cuff tears, Achilles or patellar tendinopathy, and plantar fasciitis — just to name a few — are often hearing about PRP as a potential treatment option.

But here’s something we tell our patients all the time: not all PRP is the same.

The success of a PRP treatment depends on many important details, and “success” can mean more than just short-term pain relief. For many patients, PRP can:

  • Reduce pain

  • Improve function

  • Support healing of damaged tissue

  • Slow cartilage deterioration in osteoarthritis

That’s why PRP has the potential to be disease-modifying — not just symptom-relieving.

What Details Really Matter?

Experience of the physician – How long have they been performing PRP injections?
Accuracy of the injection – Ultrasound guidance is key to making sure the PRP is delivered precisely where it’s needed.
Amount of blood drawn – Using a higher volume can help produce the optimal number of platelets.
PRP preparation – Should the PRP be rich in white blood cells or poor in them? The answer depends on your specific condition.
Medication & supplement guidance – Some should be stopped before and after the procedure for the best results.
Aftercare recommendations – Whether it’s rest, bracing, or temporary use of crutches or a boot, good guidance makes all the difference.
Number & frequency of injections – A tailored plan is essential.
Ongoing education – Physicians who teach and stay up to date on orthobiologic treatments bring that expertise to your care.
Transparency – You deserve clear communication about outcomes, expectations, and cost.

Why Choose Us?

The truth is, only a handful of physicians in Middle Tennessee take all of these details into account. That’s what sets our practice apart.

If you’re considering PRP — a natural, effective, and minimally invasive treatment — we’d love to talk with you about whether it’s the right option for you.

F. Clarke Holmes, M.D.

PRP: Natural/Holistic, Preventative & Effective

The trend we are seeing is in so many patients is their desire to treat their medical conditions with something more natural, less invasive, safe, effective and preventative. Well, platelet-rich plasma injections really check all of these boxes.

PRP injections have been a part of our treatment regimen for many conditions now for 15 years! Thus, PRP is not some trendy, gimmicky, unproven type of therapy.

If you have knee osteoarthritis and it’s not to the point of requiring a knee replacement, then PRP is probably your most effective option to relieve pain, improve function and stop or slow the deterioration of cartilage in your joint. Unfortunately, steroid (cortisone) and hyaluronic acid (the “gel” injections) do not have this preventative benefit of protecting your cartilage.

Of course, we believe in total body care, so physical therapy, bracing, weight loss, a customized exercise regimen, an anti-inflammatory pattern of eating and certain supplements can all play a very valuable role in treating your pain and osteoarthritis.

If you have a chronic tendon problem such as of the rotator cuff, the Achilles tendon, tennis or golfer’s elbow or plantar fasciitis, then PRP can actually heal these conditions. Steroid injections, on the other hand, often provide more rapid pain relief for these conditions, yet are almost always inferior to PRP injections in studies looking at these patients 6-12 months after these injections. Meaning, if your long-term goal is healing and persistent pain relief, then PRP is the better option.

Want to know more? Check out some of our blogs:

Insurance Companies Say PRP Is Experimental…We Sigh — Impact Sports Medicine & Orthopedics (impactsportsnashville.com)

Five Keys to Successful Outcomes with PRP Injections — Impact Sports Medicine & Orthopedics (impactsportsnashville.com)

PRP And The Three "Es" — Impact Sports Medicine & Orthopedics (impactsportsnashville.com)

If you want to take the next step to help yourself in 2025, then let us be of assistance to you!

F. Clarke Holmes, M.D.

Tiger Woods and You!

You or someone you know may have something in common with Tiger: plantar fasciitis. Tiger dropped out of the Masters golf tournament last weekend due to severe heel pain caused by plantar fasciitis. This all-too-common orthopedic condition afflicts a huge number of middle-aged Americans every year. The most common symptoms are heel pain when first getting out of bed, when barefoot or with prolonged walking, running or sports. Here are some key “Dos” and “Don’ts” when it comes to plantar fasciitis:

What To Do When You Have Plantar Fasciitis:

1) Seek medical attention early: We have many tools in the toolbox to treat this condition, but we first need to need to confirm the diagnosis, set-up a multi-faceted treatment plan, and guide you on your prognosis. Ultrasound, which can be done in our office, is by far the best imaging study to see the plantar fascia. This factors into our concept of PIO- Proactive Interventional Orthopedics.

2) Wear good footwear at ALL times: when in the house, in the yard, at the gym, at the pool, while shopping, going to that concert, socializing with friends and at church. Good footwear means very supportive, not too flexible, and not too cheap. Cheap unfortunately often means lower quality.

3) Consider inserts/orthotics for your shoes: over-the-counter can get the job done, but you’ll need some advice on how to choose these. A high-quality athletic shoe store or a visit to your sports medicine doctor can supply that information. However, custom orthotics prescribed by your physician may really be what you need. We are fortunate to have custom orthotic specialists that work directly with our practice.

4) Consider physical therapy as it’s beneficial for most patients: many cases of PF are related to biomechanical problems, meaning that your calves are too tight, your foot pronates or supinates, your foot muscles are weak or you are overweight. Physical therapy along with weight loss in some individuals can help correct these biomechanical problems.

5) Realize that 10-20% of cases of PF will need an advanced treatment: in our practice, our first-line innovative and advanced treatment for stubborn PF is a platelet-rich plasma injection. PRP uses your own blood and the concentrated growth factors we have produced to reduce inflammation and pain while stimulating a healing response. If this fails, then we move on to a minimally-invasive surgery called a percutaneous fasciotomy using the Tenex system.

What Not To Do When You Have Plantar Fasciitis:

1) Stretch the bottom of the foot: many cases of PF involve tears in the plantar fascia. Although stretching the calf can help, stretching the bottom of the foot often irritates the fascia and can inhibit the healing process.

2) Buy expensive orthotics that are rigid or produced by an “orthotics store”: in our experience, these tend to be very uncomfortable for patients and unsuccessful in treating patients’ symptoms. Stick with an orthotics specialist recommended by an orthopedic/sports medicine physician.

3) Have multiple steroid/cortisone injections: although offered by some orthopedic doctors and podiatrists, we rarely offer these injections for PF and essentially never do more than one. Steoid injections can contribute to further tearing and often impede healing. Some patients feel better in the short term with steroid injections, but are worse in the long term.

4) Run/Walk through the pain: unfortunately, PF will just not get better if you keep doing the things that are causing the problem. So, a period of complete rest or relative rest will be necessary for PF to improve. Relative rest can mean dialing down your walking/running frequency or distance to the point that you stay below your pain threshold.

5) Become impatient: recovery from PF is often in the range of months, not days or weeks. So, once a treatment plan is in place, you’ll have to be patient. We often construct a Plan A, Plan B and Plan C. Each plan has 2-4 treatment entities within it and we insitute these for 1-2 months, judge their success and then move on to the next plan if we are not seeing the expected results.

In summary, plantar fasciitis is a condition that requires methodical treatment under the care of an experienced physician. Don’t just trust the advice from your non-medical friend, Dr. Google or YouTube. We are always here to help!

F. Clarke Holmes, M.D.

Five Mistakes to Avoid with Plantar Fasciitis

Plantar Fasciitis is the most common cause of heel pain, most commonly seen in middle-age individuals. There are numerous treatment options, yet with our decades of experience in treating this problem, we’ve found many pitfalls, and thus, here’s a list of what NOT TO DO!

1)      Stretching the bottom of the foot. An example is when you pull the toes back towards you. Most cases of PF involve inflammation and/or tearing of the fascia. Stretching damaged or inflamed tissue is often counterproductive

2)      Pushing through the pain with exercise. If you have PF, you have to relatively rest, which may mean temporarily discontinuing running, walking, jumping, etc. or at least, reducing your distance or frequency of these activities.

3)      Skimping on shoes and/or orthotics. The old adage, “you get what you pay for…” applies here. Think of purchasing high-quality athletic and everyday shoes as well as orthotics (inserts) as an investment in your health and quality of life. At times, the more expensive orthotics are worth the extra cost.

4)      Having multiple cortisone/steroid injections. It’s probably best to avoid steroid injections altogether for PF, yet a one-time steroid injection can occasionally be indicated for the patient that is miserable due to severe heel pain. Repetitive steroid injections often result in long-term worsening of this condition.

5)       Not being patient. PF resolves in 95% of individuals with the proper customized treatment, yet it often is a 6 to 12-month process. Don’t give up on certain treatments too soon, as most interventions work gradually over weeks to months, including footwear changes, night splints, relative rest, physical therapy, orthotics and orthobiologic/regenerative injections.

If you are struggling with plantar fasciitis, then we are here to help!

Clarke Holmes, M.D.